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Welcome to Las Vegas, Nevada- the Gambling Capital of US and the City that never sleeps! So, what has this city have to do with this site. The answer is none. I just love the photo, I took during our vacation to this city a couple of years ago. In this site, you will find articles from my autobiography, global warming, senior citizens issues, tourism, politics in PI, music appreciation and articles about our current experiences as retirees enjoying the "snow bird" lifestyle between US and the Philippines. Your comments will be highly appreciated. Please do not forget to read the latest national and international news. Some of the photos and videos on this site, I do not own. However, I have no intention on infringement of your copyrights. Cheers!

Saturday, August 21, 2010

List of Hypertension Drugs-Old and New


I have high blood pressure since I was 40 years old. Thanks God with medication and a healthy life style, I am still around to write this blog. As a retired Chemist involved in the development of new drugs from FDA, I still have an undiminished interest on new drug development specially in the field of hypertension drugs. The following article is written by Richard N. Fogoros, M.D., of About.com Guide and updated updated March 01, 2010.

"The following is a list of the most common drugs and drug combinations used to treat hypertension (high blood pressure). With so many approved drugs to choose from, settling on the "best" drug(s) for you will take careful collaboration between you and your doctor.

* Here are the things you and your doctor should consider when choosing the "best" drug(s) to treat your hypertension.

In this list, the (G) indicates that a generic form of the drug is available.

Diuretics

Diuretics ("water pills") increase the amount of sodium and water excreted into the urine by the kidneys. It is thought that they lower blood pressure mainly by reducing the volume of fluid in the blood vessels.

Diuretics commonly used for hypertension:

* Acetazolamide (G) - Diamox
* Chlorthalidone (G) - Thalitone
* Hydrochlorothiazide (G) - HydroDiuril, also sold as Microzide and Esidrix
* Indapamide (G) - Lozol
* Metolazone (G) - Zaroxolyn, also sold as Mykrox

Diuretics less commonly used for hypertension:

* Amiloride hydrochloride (G) - Midamor
* Bumetanide (G) - Bumex
* Ethacrynic acid - Edecrin
* Furosemide (G) - Lasix
* Spironolactone (G) - Aldactone
* Torsemide (G) - Demadex
* Triamterene (G) - Dyrenium

Beta-blockers

Beta blockers block the effect of adrenaline on the cardiovascular system, slow the heart rate, and reduce stress on the heart and the arteries.

* Acebutolol (G) - Sectral
* Atenolol (G) - Tenormin
* Betaxolol (G) - Kerlone
* Bisoprolol (G) - Zebeta, also sold as Ziac
* Carteolol (G) - Cartrol
* Carvedilol (G) - Coreg
* Labetalol (G)- Normodyne, also sold as Trandate
* Metoprolol (G)- Lopressor, also sold as Toprol
* Nadolol (G) - Corgard
* Penbutolol - Levatol
* Propranolol (G) - Inderal, Inderal LA
* Timolol (G) - Blocadren

Calcium Channel Blockers

Calcium channel blockers can reduce blood pressure by dilating the arteries and, in some cases, reducing the force of the heart's contractions.

* Amlodipine (G) - Norvasc, also sold as Caduet and Lotrel
* Diltiazem (G) - Cardizem, also sold as Dilacor and Tiazac
* Felodipine (G) - Plendil
* Isradipine (G) - DynaCirc
* Nicardipine (G) - Cardene
* Nifedipine (G) - Procardia XL, also sold as Adalat
* Nisoldipine - Sular
* Verapamil hydrochloride - Isoptin, also sold as Calan, Verelan, and Covera

Angiotensin Converting Enzyme Inhibitors

The angiotensin converting enzyme inhibitors (the "ACE inhibitors") can lower blood pressure by dilating the arteries.

* Benazepril (G) - Lotensin
* Captopril (G) - Capoten
* Enalapril (G) - Vasotec, also sold as Vaseretic
* Fosinopril (G) - Monopril
* Lisinopril (G) - Prinivil, also sold as Zestril
* Moexipril (G) - Univasc
* Quinapril (G) - Accupril
* Ramipril (G) - Altace
* Trandolapril (G) - Mavik

Angiotensin II Receptor Blockers

The angiotensin II receptor blockers (the "ARBs") also reduce blood pressure by dilating the arteries.

* Candesartan - Atacand
* Irbesartan - Avapro
* Losartan - Cozaar
* Telmisartan - Micardis
* Valsartan - Diovan

Other, Less Commonly Used Hypertension Drugs

* Clonidine (G) - Catapres
* Doxazosin (G) - Cardura
* Guanabenz (G) - Wytensin
* Guanfacine (G) - Tenex
* Hydralazine hydrochloride (G) - Apresoline
* Methyldopa (G) - Aldomet
* Prazosin (G) - Minipress
* Reserpine (G) - Serpasil
* Terazosin (G) - Hytrin

Combination Drugs For Hypertension

* Amiloride and hydrochlorothiazide - Moduretic
* Amlodipine and benazepril - Lotrel
* Atenolol and chlorthalidone - Tenoretic
* Benazepril and hydrochlorothiazide - Lotensin HCT
* Bisoprolol and hydrochlorothiazide - Ziac
* Captopril and hydrochlorothiazide - Capozide
* Enalapril and hydrochlorothiazide - Vaseretic
* Felodipine and enalapril - Lexxel
* Hydralazine and hydrochlorothiazide - Apresazide
* Lisinopril and hydrochlorothiazide - Prinzide, also sold as Zestoretic
* Losartan and hydrochlorothiazide - Hyzaar
* Methyldopa and hydrochlorothiazide - Aldoril
* Metoprolol and hydrochlorothiazide - Lopressor HCT
* Nadolol and bendroflumethiazide - Corzide
* Propranolol and hydrochlorothiazide - Inderide
* Spironolactone and hydrochlorothiazide - Aldactazide
* Triamterene and hydrochlorothiazide - Dyazide, also sold as Maxide
* Verapamil extended release) and trandolapril - Tarka

I have tried diuretics,calcium channel blockers and beta blockers but my personal preference are the combination drugs. Again, consult your doctor for the right drug single or combination for your needs. Watch out for your diet, everything in moderation, exercise a little bit, avoid stress and hopefully you will live longer in spite of your high blood pressure.

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